The first meeting of the Clinton Church of Christ occurred during the uncertain times of World War II. Temporary dwellings dotted the landscape of Anderson County as families moved to the area to work on the secret Manhattan Project. The first worship service took place in one of these homes on February 7, 1943, with six people present: Bonnie & Iva Grissom, O.B. Trammell & son Byron, and Robert & Ariel Waters. The first preacher for the congregation was S.F. Timmerman. The next meeting place was an old union hall on Highway 25W, which they purchased in 1944. It was demolished and a new building built on the same spot three years later. By 1959, the congregation had outgrown its home. Property was purchased a short distance away at 500 North Main Street and a new building completed in 1964. The Clinton church is thought to be the oldest congregation of the Church of Christ in Anderson County.